High-Performance Liquid Chromatography (HPLC) is one of the most widely used analytical techniques, yet the theory underpinning liquid-phase separations is often poorly understood. This masterclass introduces participants to the important chemical factors that influence HPLC separations (including polarity, acid-base theory, and hydrogen bonding), chromatographic theory, troubleshooting, and method development/validation.
Each day ends with an interactive workshop session.
By the end of this three-day intensive course, you will:
You want to understand the theory behind liquid chromatography
You would like to understand how HPLC systems work
You would like to understand how HPLC systems work
You would like to improve your approach to HPLC method development
You would like to understand how problems can arise in the individual components of a HPLC system
You need to know how to approach HPLC method validation
Dr. Mark Powell brings over thirty years of senior analytical chemistry experience to this comprehensive masterclass. As a Fellow of the Royal Society of Chemistry (RSC), he has served in leadership roles including Honorary Secretary and Honorary Treasurer of the RSC's Analytical Division, where he led initiatives in continuing professional development.
His extensive industry experience spans senior analytical roles across multiple pharmaceutical companies, with direct responsibility for analytical development, method validation, and equipment qualification. In 2013, Dr. Powell founded his own consultancy to provide specialized training and consulting services to the pharmaceutical industry.
Dr. Powell's consulting work encompasses managing analytical aspects of pharmaceutical development programs during both early and late-stage development, as well as troubleshooting complex analytical problems. His training programs are highly sought after for their practical approach and real-world applicability.
Training Philosophy: Dr. Powell's teaching approach emphasizes practical application of regulatory concepts, helping participants not just understand the requirements but successfully implement them in their daily work. His extensive troubleshooting experience provides valuable insights into common challenges and proven solutions.